Preheat oven to 350°F. Lightly spray a 13x9-inch baking dish with cooking spray.
In a medium size mixing bowl toss together pretzels, 1/4 cup pecans and sugar with melted butter. Mix until fully moistened. Press pretzel mixture firmly onto bottom of prepared dish. Bake for 12 minutes or just until set. Cool completely.
In a medium size mixing bowl using an electric mixer, whip together softened cream cheese and powdered sugar until combined. Add cream and vanilla, whipping until smooth.
Fold in one 8 oz container whipped topping by hand. Spread cream cheese mixture over cooled crust. Chill while making jello topping.
In a medium size mixing bowl, mix together Jell-O mix and boiling cranberry juice OR water. Stir until completely dissolved. Add cranberry sauce. Stir until combined and cranberry sauce has melted. Chill for 30 minutes.
Pour cranberry Jell-O topping evenly over cream cheese. Use a spoon to arrange cranberries evenly on top before it sets. Chill overnight to allow it to set.
Frost the top with remaining whipped topping and sprinkle with reserved 2 Tbsp pecans. Store leftovers chilled covered with plastic wrap.
Cook's Note: You can serve this pretzel salad plain without whipped cream and pecans on top.
Notes
Nuts - Adding chopped pecans to the pretzels in the crust adds a fantastic nutty flavor to the base. You can omit the nuts or use walnuts, if preferred.
Cream Cheese - You can use Neufchatel cheese in place of full fat cream cheese.
Pineapple - You could add one 8 ounce can of well drained pineapple tidbits to the cranberry layer.
Citrus - You could add 2 tablespoons of fresh orange zest to the cranberry mixture.
Press the Crust Firmly - It's important to press the crust firmly onto the bottom of the dish before baking so it will hold together when sliced. Please note, it's not unusual for the pretzel crust to crumble a bit when cutting. This is normal, and part of the charm of this Cranberry Pretzel Salad.
Cream Cheese Layer - When spreading the cream cheese layer, make sure you take it completely to the sides of the dishto prevent the Jell-O from seeping down the sides.
Chill Thoroughly - To keep the layers separated when assembling, allow each one ample time to chill and fully set-up. Just like any Jell-O salad it's important to allow plenty of time for it to chill before cutting into pieces for serving.
Pour Gently - The cranberry Jell-O shouldn't be completely congealed before pouring on top, but it should be cool. Pour it gently so as to avoid disturbing the cream cheese layer. Use a spoon to arrange and separate the berries so they'll be in each piece before it sets up.