Preheat the oven to 350°F. Spray a 13x9-inch baking dish with butter flavored or classic nonstick cooking spray. Set aside.
Cook the cavatappi pasta in boiling salted water per the instructions on the box, until al dente. Drain well.
Meanwhile, by hand shred the asiago, Italian (or Vermont) sharp cheddar, fontina and mozzarella cheeses, into a medium size mixing bowl. Toss together until they are evenly combined.
Sauce: In a medium size heavy bottomed saucepan, melt butter over medium high heat.. Add flour stirring until flour is absorbed. Add salt, pepper, mustard and white pepper. Cook on medium heat for about 1 minute whisking constantly.
Gradually add the milk, whisking constantly. (The roux tends to stay around the edge of the pot, so be certain to incorporate all of the roux so the sauce will thicken.)
Bring to a gentle boil testing the thickness. [Add more milk 1/2 cup at a time only if the sauce needs to be thinned.]
Immediately lower the heat and allow to gently bubble on low for 5 minutes until the flour has cooked and the sauce is creamy and thickened.
To the sauce add 1/3 of the shredded cheese mixture and 1/2 cup of grated Parmesan cheese. Mix until melted and blended well.
Add drained pasta to the sauce. Stir until the pasta is evenly coated.
Pour 1/2 of the pasta into the prepared baking dish. Sprinkle with 1/3 of the grated cheese mixture. Repeat layers ending with the final 1/3 shredded cheese.
Buttered Breadcrumbs: Remove crusts from two slices of bread. Pulse bread in a food processor until it becomes fine crumbs. Mix with 1/2 cup of grated Parmesan cheese and three tablespoons melted butter.
Sprinkle the fresh buttered breadcrumbs on top of the macaroni and cheese.
Place into the preheated oven and bake for 30-40 minutes or until golden brown and bubbly, then serve.