Beef Brisket Recipe Oven
This braised Beef Brisket Recipe Oven is smothered in a rich, homemade Dr Pepper barbecue sauce for tender, flavorful results every time. Serve it as a hearty entrée or pile the shredded brisket onto toasted buns and top with creamy coleslaw for the ultimate barbecue sandwich.

Easy Barbecue Beef Brisket Recipe Oven
This tender brisket recipe is braised in the oven smothered with a homemade Dr Pepper barbecue sauce. It’s super tender and flavorful. When cooking brisket it’s important to note that it’s a lean cut of beef so don’t overcook it or it will dry out and become tough. It’s a popular smoked meat made famous in the great state of Texas and loved all throughout the South. The Dr Pepper barbecue sauce is full flavored and infuses the meat with a delicious flavor while it simmers in the oven low and slow.
Checkout this quick list of key ingredients you’ll need to make Dr Pepper Brisket Recipe Oven: (Scroll down for the full printable recipe card.)
- Beef – One 4-5 pound whole beef brisket.
- Spices – Garlic salt and black pepper.
- Dr Pepper Barbecue Sauce – Dr Pepper, combines with ketchup and chili sauce (i.e. Heinz or similar not Asian chili sauce) to give the barbecue sauce its signature flavor.
- Spices for the Barbecue Sauce – Dark chili powder, ancho chili powder OR chipotle chili powder OR paprika.
- Sugar – Light brown sugar for sweetness.
- Vinegar – Apple cider vinegar balances the sweetness of the sauce.
- Liquid Smoke – Liquid smoke mimics the flavor of the beef if it was cooked in a smoker.
- Onion and Garlic – Sweet onion and fresh garlic cloves amp up the flavor.
- Thickener – Tomato paste for thickening the cooking juices.

How to Make the Best Beef Brisket Recipe Oven
- Heat Oven – Preheat oven to 325°F.
- Season the Brisket – Season brisket on all sides with garlic salt and black pepper. Transfer to dutch oven fat side up.
- Make the Dr Pepper BBQ Sauce – Whisk together Dr Pepper, ketchup or chili sauce, brown sugar, apple cider vinegar, chili powder, ancho chili powder, liquid smoke, onion and garlic until sugar has dissolved. Pour over brisket.
- Braise the Brisket in the Oven – Cover Dutch oven with a lid or cover baking pan tightly with foil baking per the cooking time in the recipe until fork tender.
- Thicken the Sauce – Remove brisket to a platter. Place Dutch oven on stovetop. Add tomato paste to drippings stirring until fully dissolved. Repeat, as needed to thicken sauce to taste. (If using a baking pan, pour liquid into a saucepan.)
- Serve – Slice brisket across the grain, serve drizzled with dr pepper barbecue sauce
Kitchen Equipment to Make Dr Pepper Brisket Oven
- A 6 quart Dutch oven or similar size oven safe dish or deep skillet.
- Measuring cups and spoons.
- Sharp knife and chopping board.
- Balloon whisk and medium bowl to make the bbq sauce.

Recipe Variations, Tips and Substitutions
- Protein – You could use a chuck roast for this recipe. Depending on the weight it may not take as long to bake. Check it with a fork and if it easily shreds, it should be done.
- Chili Sauce – The chili sauce in this recipe isn’t Asian chili sauce. Use Heinz or a private label that you enjoy.
- Liquid Smoke – You can make this recipe without liquid smoke. Should you choose to use it, you can adjust the amount to suit your personal taste. Start with 2 teaspoons, then taste and add more from there.
- Baking Time – For this recipe it will take around 3 – 3 1/2 hours at 325°F to be fully done. Always adjust the braising time depending on the weight of the brisket used.
- Searing the Brisket – If you prefer, you can take a few minutes to sear the seasoned brisket on all sides before braising. However, this recipe produces such tender, flavorful meat that the extra step isn’t essential. If you choose to sear it, brown the brisket over medium-high heat on the stovetop, then cover it with the barbecue sauce and transfer it to the oven.
- Serving Options – Side dishes to serve with Beef Brisket: You can serve brisket with a side chopped Southern Style Cole Slaw, toasted Garlic Bread, homemade Baked Beans and sweet Corn on the Cob.
Storage and Leftovers
- Leftovers – Store leftover Dr Pepper Brisket in an airtight container chilled in the refrigerator for 3-4 days.
- Reheating – Reheat gently in the microwave in individual servings or in a preheat 325°F oven covered with foil. Don’t overcook or it will dry out.
- Freezer – Freeze leftovers for up to 2 months. Thaw in the fridge and reheat just before serving.

More Easy Beef Recipes to Make
- This Oven Braised Beef Stew is tender and full flavored.
- Slow Cooked Vegetable Beef Soup will warm you up from the inside out.
- Easy Ground Beef Stroganoff can be made for supper any night of the week.
- This puff pastry wrapped Beef Wellington will turn any meal into something special.
- Beef Pot Pie with Cheddar Biscuits is a one dish meal.
- Dump and cook Easy Beef Stew made in a crockpot.
- Barbecue Beef Tater Tot Casserole makes a filling meal the whole family will love.
- Smoked Roast Beef from The Slow Roasted Italian.

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Helpful Kitchen Items:
Dr Pepper Barbecue Beef Brisket
Ingredients
- 1 4-5 lb beef brisket fat trimmed
- 1 tsp garlic salt
- 1 tsp black pepper
- 1 12 oz Dr Pepper
- 1 1/2 cups ketchup or chili sauce (i.e. Heinz Chili Sauce)
- 1 cup light brown sugar
- 1 Tbsp apple cider vinegar
- 1 Tbsp dark chili powder
- 1 tsp ancho chili powder OR chipotle chili powder OR smoked paprika
- 2 tsp liquid smoke adjust to taste
- 1 medium onion finely diced
- 2 cloves garlic minced
- 2 Tbsp tomato paste plus additional as needed
Instructions
- Preheat oven to 325°F. Season brisket on all sides with garlic salt and black pepper.
- In a large 6-8 quart Dutch oven or deep baking pan sprayed with cooking spray, center brisket seasoned on all sides with garlic salt and black pepper.
- In a small bowl whisk together Dr Pepper, ketchup or chili sauce, brown sugar, apple cider vinegar, chili powder, ancho chili powder, liquid smoke, onion and garlic until sugar has dissolved. Pour over brisket.
- Cover Dutch oven with a lid or cover baking pan tightly with foil. Bake for 3-3 1/2 hours or until fork tender.
- Remove brisket to a platter, to rest. Place Dutch oven on stovetop. Add 2 Tbsp tomato paste, mixing until fully dissolved. Repeat, as needed to thicken sauce to taste. (If using a baking pan, pour liquid into a saucepan.)
- Slice brisket across the grain, serve drizzled with barbecue sauce.
- How to Make Beef Brisket Recipe in a Crockpot: Follow the recipe for seasoning the meat and center in a 6 quart oval slow cooker or similar. Whisk the sauce and pour over the meat. Cover and cook on low for 8-10 hours, then remove to a platter.Increase the temperature to high and follow the recipe for thickening the sauce. Slice, chop or pull apart with two forks and enjoy!
Notes
- Protein – You could use a chuck roast for this recipe. Depending on the weight, it may not take as long to bake. Check it at 3 hours with a fork and if it easily shreds, it should be done.
- Chili Sauce – The chili sauce in this recipe isn’t Asian chili sauce. Use Heinz chili sauce or a similar store brand private label that you enjoy.
- Liquid Smoke – You can make this recipe without liquid smoke. Should you choose to use it, you can adjust the amount to suit your personal taste. Start with 2 teaspoons, then taste and add more from there.
- Baking Time – For this recipe it will take around 3 – 3 1/2 hours at 325°F to be fully done. Always adjust the braising time depending on the weight of the brisket used.
- Searing the Brisket – If you prefer, you can take a few minutes to sear the seasoned brisket on all sides before braising. However, this recipe produces such tender, flavorful meat that the extra step isn’t essential. If you choose to sear it, brown the brisket over medium-high heat on the stovetop, then cover it with the barbecue sauce and transfer it to the oven.
- Serving Options – Side dishes to serve with Beef Brisket: You can serve brisket with a side chopped Southern Style Cole Slaw, toasted Garlic Bread, homemade Baked Beans and sweet Corn on the Cob.






Best brisket I’ve ever had
I’m so happy you enjoyed it, thank you!