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Grilled Spice Rubbed Pork Tenderloin

Take your grilling up a notch, with this Grilled Spice Rubbed Pork Tenderloin. Grilled to tender perfection, it’s basted with a homemade barbecue sauce for the finishing touch.

Grilled Spice Rubbed Pork Tenderloin

Easy Grilled Spice Rubbed Pork Tenderloin Recipe

This spice rubbed pork is a delicious choice during grilling season or any time of year. At our house, we never ever put the grill away.  Standing outside in the dead of winter is common practice. We think it’s worth the trouble to enjoy the grillin’ flavors that we love.  Fully loaded cornbread and my confetti corn corn and black bean medley  round it out nicely.

Step-by-step preparation images and ingredients for pork tenderloin on the grill

How to Make the Best Grilled Spice Rubbed Pork Tenderloin

This grilled pork tenderloin recipe is full throttle flavor and the grilling sauce has a sweet and spicy bite. It has a Southwestern flare, and makes a delicious pork taco or quesadilla, too.

  • Ingredients you’ll need to make tender Spice Rubbed Pork Tenderloin on the grill: 3 pounds pork tenderloin two pieces.
  • For the flavorful pork spice rub you’ll need: Olive oil or vegetable oil, brown sugar, lime or lemon juice, garlic powder or granulated garlic, onion powder, salt, dark chili powder, oregano, chipotle or ancho chile powder, paprika, ground mustard and cocoa powder.
  • The rub that I use for this grilled pork tenderloin is not a dry rub, but it has more of the texture associated with a paste. You can adapt the level of heat to your personal taste using more or less chili powder or chipotle powder.
  • I really like the robust combination of flavors, and I developed a chipotle-peach barbecue sauce just to accompany this tender grilled cut of pork.
  • If you’d like to take a shortcut with the sauce, you can baste it using your favorite prepared BBQ sauce.
  • Allow a few minutes for the pork tenderloin to rest after grilling, to allow the juices to redistribute. This will result in a more tender texture.
  • Store leftover pork tenderloin in the refrigerator for up to 3 days. Use it as a filling for quesadillas, barbecue sandwiches, for topping a baked potato with sour cream and bacon as a pizza topping and beyond.


Grilled Spice Rubbed Pork Tenderloin

Southern Style Side Dishes to Serve with Grilled Pork Tenderloin

The complementary side dish options are abundant and there are so many directions you could go. If you need a little side dish inspiration you may enjoy  trying these recipes, too:

Grilled Spice Rubbed Pork Tenderloin

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Grilled Spice Rubbed Pork Tenderloin

Prep Time10 minutes
Cook Time25 minutes
Resting time10 minutes
Total Time45 minutes
Course: Appetizer, Main Course, Pork
Cuisine: American
Keyword: barbecue-pork-recipes, grilled-pork-tenderloin, spice-rubbed-pork
Servings: 6 servings
Calories: 308kcal
Author: Melissa Sperka


  • 3 lb pork tenderloin (Packages typically come with 2 at about 1 1/2lbs/each)
  • Spice paste rub:
  • 1 Tbsp olive oil
  • 1 Tbsp brown sugar
  • 2 tsp lime or lemon juice
  • 1 1/2 tsp garlic powder
  • 1 tsp salt
  • 1 tsp onion powder
  • 1 tsp dark chili powder
  • 1 tsp dry oregano
  • 1/2 tsp ground chipotle or ancho pepper
  • 1/2 tsp ground mustard
  • 1/2 tsp paprika
  • 1/2 tsp cocoa powder
  • prepared Chipotle Peach Barbecue Sauce OR your favorite sauce


  • Place all of the paste rub ingredients into a small mixing bowl. Mixing to form ta paste.
  • Rub on all sides of the pork tenderloin, then cover with plastic wrap, and place into the refrigerator. Marinate the tenderloin at least 6 hours or overnight.
  • Remove from the fridge around 20 minutes prior to grilling to allow the meat to warm to room temperature.
  • Seer the tenderloin over high heat for 2 minutes on all 4 sides.
  • Continue to cook on the widest side for 6-8 minutes each depending on the thickness of the tenderloin. Adjust the cooking time as needed based on thickness. The tenderloin pictured were approximately 2 1/2-3 inches at their thickest. The general recommendation is to cook whole pork [not ground] to an internal temperature of at least 145°F or to medium rare.
  • Brush on the grillin' sauce during the last 3-5 minutes of grilling to char.
  • Rest loosely covered with aluminum foil for about 5-10 minutes before carving.
  • Serve with chipotle-peach barbecue grillin' sauce or your favorite bbq sauce.


Serving: 1serving | Calories: 308kcal | Carbohydrates: 3g | Protein: 47g | Fat: 11g | Saturated Fat: 3g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 5g | Trans Fat: 1g | Cholesterol: 147mg | Sodium: 513mg | Potassium: 925mg | Fiber: 1g | Sugar: 2g | Vitamin A: 191IU | Vitamin C: 1mg | Calcium: 25mg | Iron: 3mg
Tried this recipe?Mention @melissassk or tag #melissassk!


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